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KMID : 0363220170550060360
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Korean Journal of Dermatology
2017 Volume.55 No. 6 p.360 ~ p.363
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A Case of Multiple Fungal Abscesses on Inguinal Area Caused by Itraconazole-resistant Trichophyton rubrum
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Kang Hyun-Ji
Won Chong-Hyun
Chang Sung-Eun
Lee Mi-Woo
Choi Jee-Ho
Lee Woo-Jin
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Abstract
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Dermatophytes usually infect keratinized epithelial structures such as hair and nails. However, they can also cause deep and extensive fungal infections, especially in immunocompromised patients. We report a case with multiple dermal abscesses, which is a rare manifestation of Trichophyton rubrum infection. A 54-year-old man presented with multiple subcutaneous nodules in both inguinal areas with associated tinea cruris. Histopathological findings showed abscesses with fungal hyphae highlighted using Periodic acid-Schiff diastase (PAS-D) staining. Trichophyton rubrum was isolated on a fungal culture of the biopsy specimen obtained from a subcutaneous nodule in the inguinal area. The lesions were resistant to treatment with itraconazole (100 mg twice a day for 6 months); thus, we changed the drug to voriconazole (200 mg twice a day for 3 months). In addition, we extracted the remaining big lesions by incision and drainage. The patient was successfully treated with voriconazole and surgical method
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KEYWORD
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Fungal abscess, Itraconazole, Trichophyton rubrum, Voriconazole
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